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Tetrabutylammonium Iodide (TBAI)

Phase‑transfer catalyst • ammonium

Class: quaternary ammonium iodide Function: phase‑transfer catalyst • iodide source Applications: SN2/halide exchange • Williamson ether • epoxidation Also: radical mediator/photoredox additive Solubility: water, MeOH, MeCN, acetone, DCM CAS 311‑28‑4 • Non‑DG (typical)
Handling/formulation notes: Iodide can oxidize to iodine on air/light exposure—store sealed, protected from light, and consider inert gas blanketing for bulk. Use dry solvents/bases; water and strong oxidants reduce effectiveness. For biphasic PTC, agitation and base strength (e.g., 30–50% NaOH/KOH) control rate; for halide exchange, dose 5–20 mol% iodide relative to substrate.
Form
white to off‑white crystalline powder
Assay (TBAI)
≥ 99%
Water (KF)
≤ 0.5% (std.); ≤ 0.2% (low‑water)
Molecular weight
≈ 369.37 g/mol
Typical dosage*
0.5–5 mol% (PTC); 5–20 mol% (iodide)
*Optimize by solvent/temperature/phase ratio and substrate reactivity. Shipped goods conform to the lot COA.
Parameter Typical Spec
Assay (TBAI) ≥ 99% ≥ 98%
Water (KF) ≤ 0.5% ≤ 0.7%
Halides (Cl⁻/Br⁻) ≤ 500 ppm each ≤ 1000 ppm each
Appearance white/off‑white powder conforms
Melting range ≈ 147–154 °C ≥ 145 °C
Notes free‑flowing; packed under dry air
Applications Packaging Storage & Handling
• Phase‑transfer catalysis: alkylations, etherifications, esterifications.
• Halide exchange (Finkelstein), deprotection/activation via iodide.
• Epoxidations (e.g., with Oxone®), glycolate chemistry, photoredox.
• 25 kg fiber drums with PE liner.
• 1 / 5 / 10 kg HDPE bottles (powder).
• 5 / 20 kg pails • 200 kg drums (solutions).
• Hygroscopic and light‑sensitive—store sealed, cool/dry, protected from light.
• Avoid strong oxidizers; may slowly release iodine; handle with PPE.
• Non‑DG (typical) — confirm per chosen grade/route.
Compliance: Industrial/research use unless otherwise agreed. For pharma or electronic applications, request high‑purity spec and residual/trace profile. Buyer remains responsible for suitability and local regulations.

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